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TEST: Y-90 Microspheres for SIRT

1.  SIR-Spheres ®  was approved by the Food and Drug Administration as...:
        a soluble radiopharmaceutical

        a colloidal radiopharmaceutical

        an implantable radiotherapeutic device

        an unsealed source in the body

2.  The average diameter of Y-90 Microspheres is approximately...:

        0.3 mm

        3.0 mm

        30 mm

        300 mm

3.  Y-90 decays by...?:

        alpha emission

        pure beta emission

        beta/gamma emission

        electron capture

4.    The half-life of Y-90 is...?: 

        2.5 min

        2.5 hours

        2.5 days

        2.5 weeks

5.     The goal of treating liver metastases with Y-90 Microspheres is to...?

        deliver a very large radiation dose to the entire liver

        deliver a tumoricidal dose to the metastases while minimizing the dose to normal liver tissue

        shrink the tumor with an external radiation beam so it may then be removed surgically

        destroy tumor cells so a liver transplant can then be performed

6.   The number of Microspheres delivered during a typical injection number approximately...?:

        500,000

        5,000,000

        50,000,000

        500,000,000

7.   Successful administration of Y-90 Microspheres is typically  performed by...:

        a radiologist

        a nuclear physician

        a radiochemist and a nurse

        a multi-disciplinary team

8.   Therapy of liver metastases with Y-90 Microspheres is successful because which one of the following statements is TRUE?:

        80% of the blood supply to liver tumors derives from the hepatic artery and 80% of the blood supply to normal liver tissue derives from the portal vein

        80% of the blood supply to liver tumors derives from the hepatic artery and 20% of the blood supply to normal liver tissue derives from the portal vein

        20% of the blood supply to liver tumors derives from the hepatic artery and 80% of the blood supply to normal liver tissue derives from the portal vein

        20% of the blood supply to liver tumors derives from the hepatic artery and 20% of the blood supply to normal liver tissue derives from the portal vein

9.   Which ONE of the following patients is eligible to undergo Selective Internal Radiation Therapy?:

        Patient has elevated bilirubin level; shunting to lungs is 10%

          Has normal bilirubin level, lung shunting is 27%

         Has normal bilirubin level, lung shunting is 10%

        None of the above

10. The maximum % of lung shunting that is acceptable for inclusion in the study is...?

        5%

        10%

        15%

        20%  

11.  If  % of lung shunting is 15 %?

        No dose adjustment is required

        Patient study must not be performed

        Dose adjustment is required

        It is impossible to measure shunting to the lung

12.  . Which of the following is/are an eligibility requirement for participation in the study?

        Extensive angiographic workup

        Patient ineligible for liver transplant

        Good renal and hepatic function

        All of the above

13. The percent shunting to the lungs is determined by...?

        an FDG PET scan

        a lung biopsy

        a Tc-99m MAA study

        a Tc-99m Sulfur colloid study

14. The maximum tolerable radiation dose to the lungs before pulmonary fibrosis occurs is ...?

        0.3 Gy

        3 Gy

        30 Gy

        300 Gy

15. Which one of the following statements is FALSE?

        This study must be precertified by the insurance company before the dose is ordered

        Either one lobe or the whole liver may be treated

        The BSA Method of dose determination is based on the patient’s Body Surface Area as well as the % tumor involvement

        The typical dose administered is 0.1 GBq

16.      Which of the following are expected side effects of the SIRT procedure?

        Nausea

        Lethargy

        Gastritis

        All of the above
         
       
None of the above

17. Which one of the following emissions from Y-90 in the patient’s liver can be used for a post-dose image to insure correct localization...?

        High-energy b- particles

        Medium energy g-rays

        Bremsstrahlung X-rays

        Auger electrons

18. Regarding post-treatment planning, which ONE of the following is NOT recommended...?

        Single use room

        Minimize number and length of visits by friends and family

        Nursing services delivered on RIGHT side of patient

        Only non-pregnant staff/visitors present

19. After discharge, which one of the following is NOT recommended??

        antibiotic for 5 days to prevent infection

        pain medication and anti-nausea medication as needed

        patient should be well-hydrated

        patient must remain in bed for 7 days before resuming normal activities

20.  Which ONE of the following procedures is valuable for long-term follow-up of the patient ...?

        Review of patient’s medication and pain diaries

        Tc-MAA lung scan

        Tc-99m SC liver scan

        F-18 FDG PET scan

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