
1. Synthesis is based on the nucleophilic substitution with 18F -, promoted by a phase transfer catalyst.
2. The process includes the separation of the 18O from the 18F, labeling reaction, hydrolysis and finally formulation as an injectable solution.
3. Process time is < 30 min.
4. The radiochemical yield is 50 to 60 % depending on purity of starting material
5. The specific activity is >10 Ci/µmol (370 GBq/µmol)
6. The radiochemical purity is > 98.5 %.