I-123 mIBG and I-131 mIBG
Clinical Studies
Conclusions
-
Image quality of 123I mIBG is superior to that
obtained using 131I mIBG
-
Image time significantly reduced with 123I
-
Sensitivity and specificity are both >90%
Clinical Study # 1:
patient WW
- 55 y/o WM,
right adrenal mass on MRI
- history of
HTN X 15 yr
- thyroid
blocked with SSKI solution
- injected
with 0.5 mCi of I-131 mIBG
|
 |
Clinical Study # 2:
Patient EF
- 44 y/o BF
- History
of HTN, anxiety
- thyroid
blocked with SSKI solution
- injected
with 10.5 mCi of I-123 mIBG
|
 |
Clinical
Study # 3: Patient SA
- thyroid
blocked with KClO4
- 16y/o
obese WF, R adrenal mass on CT
- history
of HTN X several months
- elevated
urinary catecholamines
-
Medication: dibenzylene, 10 mg q 6 hr
- injected
with 8.5 mCi of I-123 mIBG
|
    

|
Clinical Study # 4:
Patient MR
- 35 Y/O WM
- History of
difficult-to-control HTN
- Mass seen
on CT
- thyroid
blocked with SSKI solution
-
injected
with 9.8 mCi of I-123 mIBG
|
 |
Clinical Study # 5:
Patient KT
- 60 y/o WF
- History of
pheochromocytoma 8 years prior to this study.
- Has
recurrence of HTN and other symptoms
-
Medication: beta blockers
- thyroid
blocked with SSKI solution
-
injected
with 10 mCi of I-123 mIBG
|
 |