Neuroendocrine Tumor Imaging:* ImIBG

Neuroendocrine Tumor Imaging

I-123 mIBG and I-131 mIBG Patient Utilization

PATIENT PREPARATION FOR *I-mIBG INJECTION
- Thyroid Blockage with SSKI
- For I-123 mIBG, ten drops at least 30 minutes prior to injection of mIBG and three drops once a day for three days

For I-131 mIBG, ten drops at least 30 minutes prior to the scan and three drops once a day for ten days
Patient must drink extra fluid for 24 hr post injection to minimize radiation dose to urinary bladder and gonads

ADMINISTERED DOSE
- For ¹²³I-mIBG: 5-10 mCi
- For ¹³¹I-mIBG: 0.5 mCi
DRUG ADMINISTRATION
- Inject over a two minute period
- Use a saline flush to keep butterfly open
- Observe patient for 20 minutes post injection to insure that no adverse reaction has occurred
- Release patient
IMAGING TIMES
- For I-123 mIBG: whole body scan and posterior abdominal view at 24 hr post injection; posterior abdominal view at 36-40 hr post injection
- For I-131 mIBG: whole body scan and posterior abdominal view at 48 hr post injection; posterior abdominal view at 72 hr post injection
ADVERSE REACTIONS FOLLOWING IV INJECTION OF *I-mIBG
- At our university, we have injected ~1,000 patients with no recorded adverse reactions
CONTRAINDICATIONS: DRUGS THAT BLOCK UPTAKE OF mIBG
- Cocaine
- Reserpine Alkaloids
- Phenylpropanolamine
- Tricyclic Antidepressants