Neuromuscular Tumor Imaging

•   I-123 mIBG and I-131 mIBG  
   

  • PROCEDURES THAT EXPLORE ANATOMICAL SITES
     

    • Computed Tomography and MRI
       
    • Ultrasound
       
    • Scintigraphy with *I-mIBG or ¹¹¹In Octreoscan
       
    • Arteriogram guided by norepinephrine level
       
    • Norepinephrine levels from different sites of vena cava
      
       

  • DRUG AVAILABILITY
     

    • ¹²³I-mIBG: NDA Approved; available in US as of December 2008
       
    • ¹³¹I-mIBG: NDA Approved; available in US as of June, 1994

   

  • *I-mIBG STRUCTURE
     

  
   

  •  CHARACTERISTICS OF ¹²³I AND of ¹³¹I
     

    • t_phys of ¹²³I = 13.3 hr; E_g = 159 keV
    • t_phys of ¹³¹I = 8.08 days; E_g = 364.5 keV