99mTc Sestamibi: Other Uses in Nuclear Medicine

Prognostic indicator: Breast Tumor Imaging with Tc-99m Sestamibi

• ~ 1% of injected dose localizes in the tumor
   
• Delayed views demonstrate presence of tumor
   
• May locate lesions missed on mammograms
   
• Utilized mostly for high-risk patients; not suitable for annual screening
   
• Image quality is very dependent on position of camera relative to breast
   
• Possibility of a dedicated conical shaped camera to optimize imaging

Parathyroid imaging with Tc-99m Sestamibi

• Localizes preferentially in thyroid, parathyroids, and in parathyroid adenomas
   
• Early imaging identifies thyroid, parathyroid and adenoma
   
• Delayed views demonstrate the presence of adenoma only. If subtraction technique is desired, thyroid image may be produced using I-123 sodium iodide may be subtracted.