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1. Which ONE of the following statements is true?:
Tc-99m
Sestamibi has a short biological half-life in the heart
Tc-99m
Teboroxime has a long biological half-life in the heart
Tc-99m
HMPAO has a long biological half-life in the brain
The
tbiol of Tc-99m HSA in the blood pool is >Tc-99m RBC's
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2. The renal agent Tc-99m MAG3
is cleared from the body by the following route...:
Glomerular
filtration 100%
Tubular
binding/glomerular filtration/tubular secretion, 20/40/40
Predominantly
tubular binding
Tubular
secretion/glomerular filtration 80/20
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3. The mechanism of radiopharmaceutical localization in a
ventilation study is...?:
Phagocytosis
Compartmental Localization
Active
Transport
Capillary
Blockade
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4.
The mechanism of uptake of radiopharmaceutical in liver-spleen scanning
is...?:
Particulate
blockade
Hydrolysis
of the colloid particles by the hepatocytes
Phagocytosis
by the RE system
None
of the above
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5.
Consider the following radiopharmaceuticals: Tc-99m pertechnetate,
I-123 sodium iodide, I-125 sodium iodide, and I-131 sodium iodide. Which
of them is/are suitable for thyroid imaging?
All of Them
None
of Them
Tc-99m
pertechnetate and I-123 sodium iodide only
Tc-99m
pertechnetate, I-123 sodium iodide, and I-131 sodium iodide only
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6. Which of the following
radiopharmaceuticals is suitable for blood pool scanning?:
Tc-99m
sulfur colloid
Tc-99m
tagged DTPA
Tc-99m
tagged red blood cells
None
of the above
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7. The optimal time for detection of
acute myocardial infarction by infarct avid agents is:
6
hours after onset of symptoms
24 to 72 hours after onset of symptoms
During
chest pain
One
week after onset of symptoms
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8. The
ideal diagnostic radiopharmaceutical has an effective half life of:
Of
1 day
1½ times the biological half-life
Of
6 hours
1
to 1½ times the length of time necessary to complete the test
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9.
Which ONE of the following statements regarding hepatobiliary agents is
True?:
Typical
injected dose is 3-8 mCi
In an emergency, one could substitute Tc Sulfur Colloid for Tc-DISIDA
for use in hepatobiliary imaging
If gallbladder accumulation of the DISIDA first appears on scan at 90
minutes post injection, this is a normal study
The
-IDA ending on DISIDA stands for -imidodiacetic acid
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10. Within what % of the prescribed
dose must the calibrated dose be?
5%
10%
25%
50%
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11.
Which of the following IS NOT a characteristic of
the ideal diagnostic
radiopharmaceutical?
Pure gamma emitter
100<
gamma energy <250 KEV
Effective
half life = 5 X test duration
High
target to non-target ratio
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12.
Which of the following IS a characteristic of the
ideal therapeutic
radiopharmaceutical?
Pure gamma emitter
100<
gamma energy <250 KEV
Effective
half life = 1.5 X test duration
High
target to non-target ratio
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13.
Which of these statements about radiopharmaceuticals
and radiochemicals is correct??
Radiochemicals have undergone a very lengthy and
expensive regulatory process
Radiochemicals have undergone extensive chemical and
physical testing (pH, isotonicity, and chemical parameters)
Radiopharmaceuticals
must undergo a regulatory process to guarantee safety and efficacy
Radiopharmaceuticals have been tested in animals, but
not in humans, prior to release of the product for sale.
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14.
Which one of the following series includes only
generator produced radionuclides
Tc-99m,
Ga-68, Kr-81m, Rb-82, and In-113m Tc-99m, C-11, N-13, Cr-51
Tc-99m,
Co-57, Ga-67, In-111, and Tl-201.
Tc-99m,
Xe-133, Mo-99, and I-131
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15.
Which one of the following series includes only
cyclotron produced radionuclides
Ga-68, Kr-81m, Rb-82, Tc-99m, and In-113m Cr-51, Ga-67, Tc-99m, I-131
Co-57,
Ga-67, In-111, I-123, and Tl-201
Xe-133, Mo-99, and I-131
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16.
Which one of the following statements regarding pyrogens in
radiopharmaceuticals is true?
When
injected intrathecally, pyrogens are estimated to be 1000 times as
potent as when injected intravenously
The
Limulus Amebacyte Lysate test is the least sensitive method of detecting
pyrogens
The rabbit test is the most sensitive method of
detecting pyrogens
The rabbit test is performed on serum samples
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17.
FDA regulations requires which one of the following:
Every
dose of every radiopharmaceutical must be calibrated before
administration to the patient The
administered dose must be within ±20% of the prescribed dose
Doses received from a central radiopharmacy do not have
to be calibrated
Short-lived cyclotron products are exempted from
calibration
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18.
Which one of the following series includes only
cyclotron produced radionuclides
Ga-68, Kr-81m, Rb-82, Tc-99m, and In-113m Cr-51, Ga-67, Tc-99m, I-131
Co-57,
Ga-67, In-111, I-123, and Tl-201
Xe-133, Mo-99, and I-131
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19.
Consider the following radiopharmaceuticals: Tc-99m pertechnetate,
I-123 sodium iodide, I-131 sodium iodide, and Tc-99m Myoview. Which of
them is/are suitable for thyroid imaging?
All
of them None
of them
Tc-99m pertechnetate and I-123 sodium iodide only
Tc-99m
pertechnetate, I-123 sodium iodide, and I-131 sodium
iodide only
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20.
For a patient with known pulmonary hypertension, the
number of particles of Tc-MAA should be limited to
...?
50,000 150,000
300,000
500,000
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