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1. Which
pair of the following systems is suitable for chromatographic determination of
radiochemical impurities in Tc-99m MDP?:
Silica gel/saline for free Tc,
paper/acetone for HR Tc
Silica
gel/saline for HR Tc, paper/acetone for free Tc
20% saline for free Tc, water for HR Tc
20% saline for HR Tc, water for
free Tc
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2. There are four mandatory dose calibrator tests. The
geometry test is performed at installation. What is the required frequency for
performing the other three tests?
Accuracy test daily, linearity test weekly, constancy
test monthly
Accuracy test annually, linearity test weekly,
constancy test quarterly
Accuracy test daily, linearity test quarterly,
constancy test annually
Accuracy test annually, linearity test quarterly,
constancy test daily
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3.
In the Mo-99 Breakthrough test, a technologist first measured the
Tc-99m activity of the eluate on the Tc-99m setting using the plastic holder
that drops into the calibrator. Then the Mo-99 activity was assayed in the
special lead container using the Mo-99 setting. Which of the following is an
accurate assessment of how the test was performed?
The
individual steps were performed correctly and in correct order
The individual steps were performed correctly but in incorrect order
The individual steps were performed incorrectly but in
correct order
The
individual steps were performed incorrectly and in incorrect order
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4.
Which of the following is a radionuclide impurity?
Mo-99 in the Tc-99m eluate
HR Tc in the Tc-99m eluate
Free Tc in the Tc-99m eluate
Unbound I-123 in I-123 mIBG
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5.
Which two of the following are NOT radiochemical impurities?
a.
Aluminum ion in the Tc-99m eluate
b.
HR Tc in the Tc-99m eluate
c.
Free Tc in Tc-99m MDP
d. Mo-99
in the Tc-99m eluate
a and b
b and d
ac
a and d
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6. The upper limit of Mo-99 breakthrough for a fission
Mo-99 generator is
0.15 mCi Mo-99/mCi Tc-99m at time of elution.
0.15 mCi Mo-99/mCi Tc-99m at time of administration
1.5 mCi Mo-99/mCi Tc-99m at time of elution.
1.5 mCi Mo-99/mCi Tc-99m at time of administration
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7. The amount of Hydrolyzed Reduced
Tc-99m found in preparations of Tc-MAA
is ...?
Typically <1%
Typically
between 1-3 %
Typically between 5-10%
Hydrolyzed
Reduced Tc-99m in Tc-MAA cannot be determined
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8.
Radiochemical impurities are quantitated by
Dose calibration
Gamma ray spectral analysis
Chromotography
Colorimetry
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9.
A technologist performed the Aluminum ion breakthrough
test by placing a drop of an aluminum standard solution on one end of the
special test paper and a sample of the Tc-99m eluate on the other end of the
test strip. The eluate spot turned a medium red color and the standard
solution turned the paper a faint pink color. Which of the following is
correct:
The test was performed incorrectly and therefore
results are invalid
The test was positive for aluminum ion
breakthrough
The test was negative for aluminum ion
breakthrough
The test should have been performed using a dose
calibrator
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10. For
radioisotope dose calibrator quality control tests,
Measured values must be within 5% of the expected
values
Measured values must be within 10% of the expected
values
Measured values must be within 15% of the expected
values
The value is set independently by each laboratory
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