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1. The least optimal method of RBC
labeling with Tc-99m for performing a GI Bleeding study is the...?:
Ultratag method
In
vivo/in vivo
In
vivo/in vitro method
In
vitro/in vitro method
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2. An Ultratag kit for RBC labeling
typically produces a labeling efficiency of approximately...?:
70%
80%
90%
>95%
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3. Tc-99m Ceretec is used for preparation of Tc-WBC because it...?:
Is hydrophilic and is therefore
unable to cross the membrane of the WBC, but can bind to its surface
Is
lipophilic and therefore easily crosses the lipid membrane of the WBC,
permitting binding inside the WBC
Is hydrophilic and therefore
easily crosses the lipid membrane of the WBC, permitting binding inside the
WBC
Is lipophilic and is therefore
unable to cross the membrane of the WBC, but can bind to its surface
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4.
In quality control testing of Tc-WBCs, trypan blue dye is used to...?:
Measure radiochemical purity
Determine radionuclidic purity
Measure
cell viability
Stabilize the preparation prior to
injection
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5.
When preparing Tc-RBC’s, the reducing agent used contains?:
Mercurous ion
Ferrous ion
Stannic ion
Stannous
ion
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6. The molecule to which reduced
Tc-99m binds is hemoglobin. To which part of this molecule is the Tc bound?:
a-globin
chains
b-globin
chains
g-globin
chains
Central heme portion
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7. In the in vivo/in vivo procedure, these terms refer respectively, to...?:
Where reducing agent is stored
/ where the Tc-99m is stored
Where the Tc-99m is stored / where reducing agent is stored
Where
reduction takes place / where radiolabeling takes place
Where radiolabeling takes place
/ where reduction takes place
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8.
In adults, the required amount of Sn2+ required for
effective red cell labeling with Tc-99m is?:
1
mg
10
mg
100
mg
1000
mg
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9.
To successfully radiolabel RBCs with Cr-51, one mixes Cr-51 Na chromate
with...?:
Anticoagulated
blood and incubates for 20 minutes
Non-coagulated blood and incubates for 20 minutes
Serum obtained from a clotted blood sample for 20 minutes
Anticoagulated whole blood
preheated at 50ºC for 20 minutes
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10. To determine RBC labeling
efficiency, a sample of blood containing Tc-labeled RBCs is spun in a
microhematocrit tube. The tube is then broken at the dividing line between the
plasma and the packed cells and the two halves are counted. Which of the
following fractions is used to determine the labeling efficiency?:
Activity in plasma / activity
in red cells
Activity in red cells / activity
in plasma
Activity in plasma / activity
in red cells + plasma
Activity
in red cells / activity in red cells + plasma
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