SIR-Spheres:
A New Treatment Option for
Non-Resectable Liver Tumors

• Treatment Overview
  • SIRT: Selective Internal Radiation Therapy
    • Concept of SIRT
    • Science & Specifications of SIR-Spheres
• Published Outcomes
• Patient Selection
• Treatment Planning
  • Pre-Treatment Testing
  • Treatment Issues
    • MAA Spect
    • Dosimetry
    • Administration Technique
    • Side Effects
    • Discharge
    • Radiation Safety
• Clinical Studies

SIRT Advantages

• Sphere treatment is a minimally invasive procedure and is usually performed as an outpatient procedure

• Spheres are reimbursed by Medicare when delivered as an outpatient procedure

• Spheres offer patients who have unresectable metastatic tumors an alternative therapy to prolong survival.

• SYS chemotherapy can resume 4 weeks after treatment

• Sphere treatment can downstage tumors and allow for surgical resection

Conclusions:

• All patients with liver cancer are potential candidates for SIRT

• SIRT needs a team for effective treatment

• SIR-Spheres are an adjunct to, not a replacement, for chemotherapy. The earlier in the treatment process, the better the outcomes

• SIR-Spheres are active against all tumor sizes

• Patient may be downstaged to resection following treatment

SIR-Spheres* Trademarked by SIRTEX SIR Spheres PTY Ltd