Part 8: In Vivo Non-Imaging Studies

1.   Which one of the following is NOT an example of an in vivo non-imaging procedure?

      a. a radioimmunoassay

      b. a splenic sequestration study

      c. a Schilling Test

      d. a Thyroid Uptake Test

2. The typical injected dose of Cr-51 RBCs is

a.      0.0075 mCi

b.      0.075 mCi

c.      0.75 mCi

d.      7.5 mCi

3.      The normal value for half-time of survival of Cr-51 RBCs is

a.      approximately 30 days

b.      approximately 60 days

c.      approximately 90 days

d.      approximately 120 days         

4.      A splenic sequestration study was performed. A Spleen/Liver Ratio of 2.8:1 was obtained. The diagnosis would be

a.      Normal study

b.      Very small spleen

c.      Slightly enlarged spleen

d.      Significant splenic sequestration

5.      A Plasma volume/Red Cell Mass Study is useful

a.      to measure hematocrit

b.      to diagnose Polycythemia Vera

c.      to evaluate renal function

d.      to diagnose pernicious anemia

6.      A Plasma Volume Study is based on the principle of

a.      reverse transition

b.      isotope dilution

c.      reverse isotope dilution

d.      plasma dilution

7.      The results of a RCM/Plasma Volume study

      

 

 

 

 

are shown above. The diagnosis is:

a.      Normal study

b.      Dehydration

c.      Polycythemia Vera

d.      Pernicious anemia

8.      The administered activity of radiocobalt in a Schilling Test is approximately

a.      0.5 mCi

b.      5 mCi

c.      50 mCi

d.      500 mCi

9.      The Schillling Test is used to diagnose

a.      Pernicious anemia

b.      Hyperthyroidism

c.      Polycythemia

d.      Plummer’s Disease

 

10.      In the Schilling Test, an IM injection of 1 mg of non-radioactive B12 is given to

a.      Reduce radiation dose to the liver

b.      Increase urinary output

c.      Saturate binding sites in the liver

d.      Increase binding of radiocobalt B12 to intrinsic factor

11.      Patient X has a deficiency of intrinsic factor in his gut. The expected result of Stage 1 of a Schilling Test would be a % excretion of the radiocobalt in the range of

a.      0-6%

b.      6-10%

c.      10-30%

d.      80-90%

12.  The result of a dual Schilling Test was 14.1% excretion of Co-57 and 13.9% excretion of Co-58. The diagnosis is

 

a.      pernicious anemia

b.      simple malabsorption syndrome unrelated to intrinsic factor deficiency

c.      normal study

d.      impossible to make without first administering an antibiotic and then repeating the study 2 weeks later

13.  The typical administered dose of I-123 NaI for performing an RAIU is

a.      0.2 mCi

b.      2 mCi

c.      20 mCi

d.      200 mCi

14.  The typical administered dose of I-131 NaI for performing an uptake and scan in a patient with a substernal thyroid is

a.      0.1 mCi

b.      1 mCi

c.      10 mCi

d.      100 mCi

15.  Which of the following is NOT a required part of the preparation for an RAIU?

 

a.      Discontinue synthroid for 4 weeks prior to performing RAIU

b.      Patient must be NPO from midnight until 1 hour post administration of I-123 NaI

c.      Patient must discontinue propranolol for 4 weeks prior to performing RAIU

d.      Patient must not have undergone CT Scan with Contrast Media

16.  A patient underwent an RAIU and the result was 58.4%. The diagnosis is

a.      Normal

b.      Hypothyroid

c.      Hyperthyroid

d.      Hashimoto’s thyroiditis

 


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