Part 10: Radionuclide Therapy

1.      The appropriate dose of I-131 NaI for treatment of a "hot nodule" is

a.      1 mCi

b.      5 mCi

c.      8 mCi

d.      25 mCi

2.      The appropriate dose of I-131 NaI for treatment of Graves disease is

e.      1 mCi

f.        5 mCi

g.      8 mCi

h.      25 mCi

3.      Which 2 of the following types of thyroid cancer are treatable with radioactive iodide?

a.      anaplastic

b.      medullary

c.      follicular

d.      papillary

4.      Patients undergoing therapy for polycythemia are treated with

a.         P-32 sodium phosphate

b.         Cr-51 sodium chromate

c.         P-32 chromic phosphate colloid

d.         Cr-51 chromic phosphate colloid

5.      Which one of the following isotopes is not suitable for performing radionuclide therapy?

a.      I-131

b.      P-32

c.      I-123

d.      Sm-153

6.      The release criterion for a patient who has received a high dose of I-131 NaI is

a.      5 mR/hr at 1 meter

b.      50 mR/hr at 10 cm

c.      50 mR/hr at 1 meter

d.      5 mR/hr at the body surface

e.      None of the above

7.      Patients treated with I-131 NaI for Graves disease experience maximum beneficial effects

a.      1 week after treatment

b.      1 month after treatment

c.      3 months after treatment

d.      6 months after treatment

8.      Mark the following statements regarding I-131 NaI therapy True/False

a.      I-131 NaI therapy for Graves disease is rarely curable

b.      Men with Graves disease are more difficult to treat than women

c.      A suitable first dose for treating thyroid Ca is 50 mCi

d.      After effective therapy of a hot nodule, normal function returns to the rest of the thyroid glad.

9.      To what does the TDS Concept refer?

10. The most common side effect of treatment of Graves disease with I-131 NaI is

a.      Thyroid cancer

b.      Hashimoto's disease

c.      Development of hot modules

d.      Goiter

e.      None of the above

11.  Mark the following statements True/False

a.      Sr-90 chloride is frequently used for palliation of pain from bony metastases.

b.      Strontium therapy may be performed in patients with metastases from any primary malignancy

c.      A long term side effect of successful treatment of p. vera with P-32 is multiple myeloma

d.      Bexxar and Zevalin are used to treat patients with leukemia

12. The radiation dose to the thyroid gland following administration of 10 mCi of I-131 to a hyperthyroid patient is approximately

a.      1 Rad

b.      10 Rads

c.      100 Rads

d.      1,000 Rads

e.      10,000 Rads